The CBC with Peripheral Smear (CBC with PS) is a comprehensive blood test that evaluates red blood cells, white blood cells, platelets, and blood cell morphology. It combines an automated Complete Blood Count (CBC) with a Peripheral Smear (PS) examination, allowing doctors to assess blood cell numbers, size, shape, and appearance under a microscope.
This test helps diagnose anemia, infections, blood disorders, nutritional deficiencies, platelet abnormalities, and certain hematological diseases.
1.Hemoglobin (Hb)
Oxygen-carrying protein in red blood cells; low levels point to anemia.
2.RBC Count (Red Blood Cell Count)
Number of red blood cells that carry oxygen around the body.
3.WBC Total Count (Leucocyte Count)
Total white blood cells, which fight infection; raised or lowered in infections and blood disorders.
4.Platelet Count (Thrombocyte Count)
Number of platelets that help blood clot and stop bleeding.
5.PCV (Hematocrit)
Percentage of blood volume made up of red blood cells.
6.MCV (Mean Corpuscular Volume)
Average size of red blood cells; helps classify the type of anemia.
7.MCH (Mean Corpuscular Hemoglobin)
Average amount of hemoglobin in each red blood cell.
8.MCHC (Mean Corpuscular Hemoglobin Concentration)
Average concentration of hemoglobin in red blood cells.
9.RDW (Red Cell Distribution Width)
Variation in red blood cell size; raised in nutritional deficiencies.
10.RDW-CV
Coefficient of variation of red cell size, another measure of size variation.
11.Neutrophils
White cells that fight bacterial infections (percentage).
12.Lymphocytes
White cells that fight viral infections and support immunity (percentage).
13.Monocytes
White cells that clear debris and fight chronic infections (percentage).
14.Eosinophils
White cells involved in allergies and parasitic infections (percentage).
15.Basophils
White cells involved in allergic reactions (percentage).
16.Absolute Neutrophil Count (ANC)
Actual number of neutrophils; shows the body's ability to fight bacterial infection.
17.Absolute Lymphocyte Count (ALC)
Actual number of lymphocytes in the blood.
18.Absolute Monocyte Count
Actual number of monocytes in the blood.
19.Absolute Eosinophil Count
Actual number of eosinophils; raised in allergy and parasitic infection.
20.Absolute Basophil Count
Actual number of basophils in the blood.
21.Platelet Distribution Width (PDW)
Variation in platelet size.
22.Mean Platelet Volume (MPV)
Average size of platelets; reflects platelet production.
23.Plateletcrit (PCT)
Percentage of blood volume occupied by platelets.
24.Platelet Large Cell Ratio (P-LCR)
Percentage of large platelets in the blood.
25.Platelet Large Cell Count (P-LCC)
Number of large platelets in the blood.
26.Platelet Morphology
Microscopic review of platelet size, shape and distribution on the smear.
27.RBC Morphology
Microscopic review of red cell size and shape; helps identify anemia types and deficiencies.
28.WBC Morphology
Microscopic review of white cells; detects abnormal or immature cells.
29.Mentzer Index (MCV/RBC)
Calculated ratio that helps tell iron deficiency anemia from thalassemia trait.
Also known as: CBC with PS, Complete Blood Count with Peripheral Smear, Hemogram with Peripheral Smear, CBC Blood Test with Smear
The CBC with Peripheral Smear (PS) provides detailed information about the health of blood cells. While the CBC measures the quantity of different blood cells, the peripheral smear allows a laboratory specialist to examine their size, shape, and structure under a microscope.
The test evaluates:
It is one of the most commonly requested investigations for evaluating general health and diagnosing blood-related disorders.
The test consists of two major components:
Complete Blood Count (CBC):
A CBC with Peripheral Smear Test may be recommended for:
The CBC with PS Test requires a blood sample collected from a vein.
Before the test:
| Parameter | Normal range |
|---|---|
| Hemoglobin | Men 13–17 g/dL, Women 12–15 g/dL |
| RBC Count | Men 4.5–5.9 million/µL, Women 4.1–5.1 million/µL |
| WBC Count | 4,000–11,000 cells/µL |
| Platelet Count | 150,000–450,000 cells/µL |
| PCV (Hematocrit) | Men 40–50%, Women 36–46% |
| MCV | 80–100 fL |
| MCH | 27–33 pg |
| MCHC | 32–36 g/dL |
| RDW | 11.5–14.5% |
| Neutrophils | 40–70% |
| Lymphocytes | 20–40% |
| Monocytes | 2–10% |
| Eosinophils | 1–6% |
| Basophils | 0–1% |
| Peripheral Smear findings | |
| RBC Morphology | Normal |
A CBC with Peripheral Smear is a blood test that combines a Complete Blood Count with microscopic examination of blood cells to evaluate blood health and detect abnormalities.
No, fasting is generally not required unless your doctor has advised additional fasting tests.
A Peripheral Smear allows laboratory experts to examine the size, shape, and appearance of blood cells, helping detect abnormalities that may not be identified by automated analyzers.
It can help diagnose anemia, infections, nutritional deficiencies, platelet disorders, blood cancers, bone marrow disorders, and other hematological conditions.
| Test name | CBC with Peripheral Smear (CBC with PS) Test |
|---|---|
| Location | Ahmedabad |
| Sample type | Blood |
| Number of parameters | 29 |
| Home sample collection | Available |
| Fasting | Not required |
| Report time | Within 24 hours |
| Recommended age | 1–99 years |
| Suitable for | Male & Female |
Peripheral Smear (PS):
A thin layer of blood is examined under a microscope to evaluate:
The Mentzer Index included in this profile also helps differentiate iron deficiency anemia from thalassemia trait when interpreted with other blood parameters.
Doctors may recommend a CBC with PS Test to:
The test may be advised if you experience:
Benefits of the CBC with Peripheral Smear Test:
| WBC Morphology |
| Normal |
| Platelet Morphology | Normal |
| Note | Reference ranges may vary between laboratories depending on age, sex, testing methods, and clinical conditions. Results should always be interpreted by a qualified healthcare professional. |
Reference ranges can differ between labs. Your report shows the range used by the lab.
The Mentzer Index (MCV/RBC) is a calculated value that helps differentiate iron deficiency anemia from thalassemia trait when interpreted with other laboratory findings.
Abnormal blood cells identified on the CBC and Peripheral Smear may suggest leukemia or other blood disorders. However, additional specialized tests are required to confirm the diagnosis.
Most laboratories provide CBC with Peripheral Smear reports within 24 hours, although reporting time may vary depending on the laboratory.
